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2-Methoxyestradiol (2-MeOE2)
SPC-00042
CAS No. 362-07-2
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| 300 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
HIF inhibitor ; Microtubule Associated modulator ; Apoptosis related activator ; Autophagy activator
| Description |
|---|
| 2-Methoxyestradiol (2-MeOE2, NSC 659853) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines. Phase 2. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 362-07-2 |
| Description | 2-Methoxyestradiol (2-MeOE2, NSC 659853) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines. Phase 2. |
| Formula | C19H26O3 |
| Molecular Weight | 302.41 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC 659853 |
| SMILES | CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.